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Get Antioxidants From Food, Not Vitamin Supplements, Says American Heart Association
Aug. 3, 2004 DALLAS (American Heart Association) -- Research fails to justify routine use of vitamin antioxidant supplements to prevent or treat cardiovascular disease, according to an American Heart Association science advisory published in today's issue of Circulation: Journal of the American Heart Association.
"At this time, there is little reason to advise that individuals take vitamin supplements to reduce their risk of cardiovascular disease," said Penny Kris-Etherton, Ph.D., lead author of the association panel, and Distinguished Professor of Nutrition in the Department of Nutritional Sciences at the Pennsylvania State University.
A review of research conducted on antioxidants between 1994 and 2002 showed that vitamin supplements largely have no effect on preventing or treating cardiovascular disease.
The American Heart Association continues to promote a diet rich in fruits, vegetables, whole grains, fish, legumes, poultry and lean meats to derive antioxidant benefits. "While the research shows that vitamin supplements have no benefit, the role oxidative stress plays in the development and progression of heart disease has yet to be clarified," Kris-Etherton said. "We still know too little about the oxidative mechanisms in humans and lack biochemical markers with which to evaluate antioxidants."
Ongoing studies should answer important questions about the role of oxidation in atherosclerosis, she said. Until those questions are resolved, this review presents the current science and helps clinicians understand that they should not recommend vitamin supplements to reduce the risk of cardiovascular disease. "We know that diets high in fruits and vegetables are associated with decreased risk of cardiovascular disease. Thus, following a diet consistent with the American Heart Association's dietary guidelines is recommended. In addition, achieving and maintaining a healthy body weight and being physically active are important to reduce cardiovascular disease risk," Kris-Etherton said.
The antioxidant vitamin studies reviewed fell into three headings: no effect on cardiovascular patients, adverse effects on cardiovascular patients, and beneficial effects on cardiovascular patients. The majority of the studies found antioxidants have no effect on cardiovascular patients.
Most of the patients in the studies reviewed were either heart patients or considered candidates for cardiovascular disease. As such, some patients were taking drugs to treat abnormal lipids and high blood pressure.
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